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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP2A1 All Species: 41.21
Human Site: S493 Identified Species: 82.42
UniProt: O14983 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14983 NP_004311.1 1001 110252 S493 E F S R D R K S M S V Y C S P
Chimpanzee Pan troglodytes XP_001142958 1000 109764 S492 E F S R D R K S M S V Y C S P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_849777 993 109198 S493 E F S R D R K S M S V Y C S P
Cat Felis silvestris
Mouse Mus musculus Q8R429 994 109407 S493 E F S R D R K S M S V Y C S P
Rat Rattus norvegicus Q64578 994 109391 S493 E F S R D R K S M S V Y C S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505463 1167 128710 S663 E F S R D R K S M S V Y C T P
Chicken Gallus gallus P13585 994 109005 S493 E F S R D R K S M S V Y C S P
Frog Xenopus laevis NP_001080404 996 109455 S493 E F S R D R K S M S V Y C T P
Zebra Danio Brachydanio rerio NP_001007030 994 108738 S493 E F S R D R K S M S V Y C S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P22700 1020 111683 S493 E F S R D R K S M S S Y C T P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SY55 998 109042 T490 K V Y V L E F T R D R K M M S
Baker's Yeast Sacchar. cerevisiae P13586 950 104552 V472 I R N T V Q K V Q E L P F N S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96 N.A. 95.5 N.A. 95.9 96 N.A. 71.1 90.2 89.1 85.2 N.A. 69.8 N.A. N.A. N.A.
Protein Similarity: 100 97.1 N.A. 98 N.A. 97.9 98 N.A. 79 95 95.5 92.2 N.A. 81.3 N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 93.3 100 93.3 100 N.A. 86.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 93.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 55.5 31.9 N.A.
Protein Similarity: N.A. N.A. N.A. 71.2 52.2 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 84 0 0 % C
% Asp: 0 0 0 0 84 0 0 0 0 9 0 0 0 0 0 % D
% Glu: 84 0 0 0 0 9 0 0 0 9 0 0 0 0 0 % E
% Phe: 0 84 0 0 0 0 9 0 0 0 0 0 9 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 0 0 0 0 92 0 0 0 0 9 0 0 0 % K
% Leu: 0 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 84 0 0 0 9 9 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 0 9 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 84 % P
% Gln: 0 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % Q
% Arg: 0 9 0 84 0 84 0 0 9 0 9 0 0 0 0 % R
% Ser: 0 0 84 0 0 0 0 84 0 84 9 0 0 59 17 % S
% Thr: 0 0 0 9 0 0 0 9 0 0 0 0 0 25 0 % T
% Val: 0 9 0 9 9 0 0 9 0 0 75 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 0 84 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _